Thesis 2009

Gastric Acid Secretion and Peptic Ulcer due to H. Pylori.

2024-09-12T07:08:43Z

Gastric Acid Secretion and Peptic Ulcer due to H. Pylori. Islam, Md. Syful Ulceration is a of the fornation of an ulcer in body. Gastric acid mediating ulcer is caned peptic ulcer. This acid is generating by a physiological pathway with the help of different and secretomotors. When ulceration is complete in GIT, a pathological condition is creating. This condition called peptic ulcer. Gastric acid normally according to the need the body. help of pump secretes the acid The source the gastric acid (H􀂺) is the dissociation the carbonic acid. Carbonic acid is produce by the hydration of the carbon dioxide with the The main for inhibiting acid IS secretomotor and in the inhibition or she been exposing to inactivation of activities of the proton pump This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.

Market Feasibility Study of Rabeprazole Sodium

2024-09-12T07:08:31Z

Market Feasibility Study of Rabeprazole Sodium Das, Bipon Chandra A peptic ulcer is damage to the lining of the stomach, duodenum, or esophagus due to corrosion caused by gastric acid or digestive juices secreted by stomach cells. Among all classes of drugs, proton pump inhibitors are the most effective for the management of peptic ulcer diseases. Rabeprazole sodium is one of the prominent proton pump inhibitors. It is commonly used in the world for the treatment of peptic ulcer. It functions by inhibiting the enzyme W /K+ ATPase which is responsible for the secretion of gastric acid. The purpose of this study is to analyze the market feasibility study of Rabeprazole sodium. Many books, journals and different articles were used to know efficacy and safety profile of drugs. Rabeprazole sodium blocks acid production in the stomach. It is prescribed for the short-term (4 to 8 weeks) treatment of sores and inflammation in the upper digestive canal (esophagus). It is more effective in the treatment of duodenal ulcer, H. pylori, gastric ulcer, erosive esophagitis, GERD, and pathological hypersecretory conditions, including Zollinger-Ellison syndrome. By the study of market, feasibility among all PPls Rabeprazole market value is 26,568,572 taka. Rabeprazole market growth is 2.29%, which is comparatively less among other PPls. To increase overall market growth I can introduce Rabeprazole sodium, which is a delayed-release tablet. Because of its D-R property I hope that with in one year it will become a superior drug for the ,treatment of peptic ulcer. This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.

Symptoms and Treatment Profile of Diarrheal Disease below Six Month Infants with or without Antibiotic Admitted to, Institute of Child Health and Shishu Sasthya Foundation Hospital (ICH & SSF)

2024-01-11T05:25:39Z

Symptoms and Treatment Profile of Diarrheal Disease below Six Month Infants with or without Antibiotic Admitted to, Institute of Child Health and Shishu Sasthya Foundation Hospital (ICH & SSF) Akhter, Dilruba Diarrhea is one of the principal causes of morbidity and mortality among children in the developing world and is the second leading killer of children under the age of five years, accounting for approximately 1.6 million deaths annually. An estimated 17 percent of the annual 10.8 million deaths in children aged less than five years are estimated to be caused by diarrhea. While international programs encouraging the use of oral rehydration therapy (ORT) and other interventions have helped to lower these rates, diarrheal disease remains a very serious public health issue for children across the globe. Recently, strong evidence demonstrating the effectiveness of new, low osmolarity ORS and zinc supplementation catalyzed an international call to action urging countries to adopt new treatment guidelines and increase efforts to improve ORS coverage. At the end of 2007, 34 Countdown priority countries had adopted both new guidelines and 17 more had adopted one or the other. The aim of this study was to get information of young children below six months with diarrhoea admitted to Institute of Child Health and Shishu Sasthya Foundation Hospital (ICH & SSF) about their symptoms and treatment profile. Hospital records of eighteen children aged below six months admitted to ICH & SSF reviewed for the purpose of getting information about the symptoms and treatment profile for those infants. The common symptoms of the study infants were loose watery stool, fever, cough, vomiting, swelling, etc. Most of the patients were treated with KOLORIDE infusion which is a balanced combination of electrolytes, ORS and some patients were kept under NPO (nothing per oral) for sometime. Among 18 patients, only 2 children received antibiotic therapy. The common antibiotics used for treating the patients were ciprozoid (ciprofloxacin) and Civox (ciprofloxacin). The result of this study shows that the symptoms of the patients disappeared after receiving the appropriate treatment. This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.

An Investigation on Antinociceptive Effect of Abroma Augusta Linn. (Sterculiaceae)

2023-07-31T03:38:33Z

An Investigation on Antinociceptive Effect of Abroma Augusta Linn. (Sterculiaceae) Ahmed, Gias Uddin Abroma augusta Linn (Sterculiaceae), commonly known as Ulatkambal(Bengali). This plant is used as medicinal plant for its distinct pharmacological activity. Chemical analysis of this p lant has noticed various chemical properties. The aim of this study was to investigate the antinociceptive effect of the ethyl acetate extract of A.augusta in acetic acid-induced writhing test in mice. The result suggests that the extract has exhibited significant (p<0.05) analgesic effects, which we ' re comparable with standard drugs. The bark extracts at 500 and 250 mg/kg showed significant reduction in acetic acid induced writhing in mice with a maximum effect of65.27% reduction at 500 mg/kg dose. This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.