Abstract:
Background: Ibuprofen (Propionic Acid derivative) is widely used for treating fever in children.
Like Paracetamol , aspirin, and physical methods (such as fanning), Ibuprofen aims to provide
relief from symptoms and prevent febrile convulsions. Objectives: To assess the effect of liquid
ibuprofen for remission of fever in hospitalized children aged greater than 4 year. Materials and
methods: Thirty-two subjects aged less than 1 year admitted to the Institute of Child Health and
Shi shu Sasthya Foundation Hospital (ICH&SSF) were included in this study. The body
temperature of the patients was recorded at different time interval before and after administration
of Ibuprofen preparation. The patients were given 5 to lO-mg/kg dose of liquid Ibuprofen. Body
temperature was recorded by thermometer after 15, 30, 60, 90, 120, 150 and 180 minutes of the
administration of liquid Ibuprofen. Data analysis: Data were analyzed by using Paired sample
T -test. Result: After administration of liquid Ibuprofen the body temperature of the patients
-tarts to reduce from 102°F to 99. 12°F. It takes about 2 hours to decrease the body temperature
nd after 3 hours the body temperature increases to 99.50F. Conclusion: Liquid preparation of
[ ibuprofen has effect of lowering body temperature of the febrile children.
: - y words: Ibuprofen, Febrile, convulsions, liquid preparation, T -test.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.
