Abstract:
The crude methanolic extracts and buffer extracts derived from the Nyctanthes arbortristis, Tinospora tomentosa & Musa sapientum Var. sylvestris were screened in vitro for possible phytochemical, antibacterial and biomedical activities. Under phytochemical analysis, antioxidant test & Chemical screening was done whereas in biomedical analysis haemolytic activity & haemagglutination test was performed.
Moderate antioxidant property found in case of banana & night jasmine, whereas for Tinospora tomentosa it was very poor. The crude methanolic extract of banana & night jasmine showed good antibacterial activity against different type of bacterias. The aqueous fractions of Tinospora tomentosa showed high activity against different type of bacterias. High haemagglutination activity was observed against human red blood cells (RBCs) of all positive group bloods by crude methanolic extract of banana & night jasmine and aquous fraction of Tinospora tomentosa. The crude methanolic extract of banana & night jasmine also showed to have prevented haemolysis of RBCs. Hence the plant species can be a source of antibacterial agent(s) and antioxidant agents as well as these plants (methanolic extract of banana & night jasmine) have good property to prevent haemolysis & have high haemagglutination activity.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) of East West University, Dhaka, Bangladesh.
