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Cytotoxic and antioxidant activity in aqueous fraction of Opuntia elatior extract

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dc.contributor.author Alam, Md. Sahibul
dc.date.accessioned 2016-03-30T05:07:49Z
dc.date.available 2016-03-30T05:07:49Z
dc.date.issued 12/15/2015
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/1693
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh. en_US
dc.description.abstract The purpose of the study was to evaluate the cytotoxic and antioxidant activity of aqueous fraction of Opuntia elatior (Family: Cactaceae) extract. The powdered of Opuntia elatior were extracted with methanol and then partitioned with pet-ether, DMSO, ethyl acetate and crude fraction was taken for experiment. The aqueous fraction was used to evaluate cytotoxic and antioxidant activities. The cytotoxic activity was measured by brine shrimp lethality bioassay. LC50 value of aqueous fraction of Opuntia elatior was 12.5µg/ml in brine shrimp lethality test. The fraction contained 12.315 mg AAE/g of total phenolic content, 30.5 mg AAE/g of total reducing power content and 56 mg AAE/g total flavonoid content. The results of study clearly indicate the presence of cytotoxic and poor antioxidant properties of aqueous extract. The obtained results provide a support for the use of this plant in traditional medicine and its further investigation. en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;PHA00408
dc.title Cytotoxic and antioxidant activity in aqueous fraction of Opuntia elatior extract en_US
dc.type Thesis en_US


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