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Cytotoxic and Anti-oxidant Activity of Petroleum Ether Fraction of Mentha ArvensisLeaf Extract

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dc.contributor.author Sultana, Afruja
dc.date.accessioned 2016-09-21T03:13:29Z
dc.date.available 2016-09-21T03:13:29Z
dc.date.issued 7/21/2016
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/1822
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh en_US
dc.description.abstract The plant Mentha arvensis has been used for the general promotion of health and longevity by Asian tribal. It is used as a traditional medicine for the treatment of various diseases like asthma, piles, diarrhea etc. The aim of the present study was to evaluate the cytotoxicity activity, and antioxidant activity of pet-ether extract of Mentha arvensis. The powdered leaves of Mentha arvensis were extracted with methanol and then partitioned with pet-ether, ethyl acetate and dichloromethane consecutively. The pet-ether fraction was used to evaluate cytotoxic, and antioxidant activities. The cytoxic activity was measured by brine shrimp lethality bioassay. Pet-ether fraction showed cytotoxic activity with LC50 value 17.79μg/ml in brine shrimp lethality test. The fraction contained 12.315mgAAE/g of total phenolic content and 56mg AAE/g total flavonoid content and 27.5mg AAE/g total reducing power content. The results of study clearly indicate the presence of cytotoxic, and antioxidant properties of pet-ether extract. The obtained results provide a support for the use of this plant in traditional medicine and its further investigation. en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;PHA00463
dc.subject Mentha arvensis, Cytotoxic test, Anti-oxidant test, Phenolic content, Flavonoid content, Reducing power assay en_US
dc.title Cytotoxic and Anti-oxidant Activity of Petroleum Ether Fraction of Mentha ArvensisLeaf Extract en_US
dc.type Thesis en_US


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