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Drug Discovery Targeting Proteomic Approach

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dc.contributor.author Rinta, Samiya Khondaker
dc.date.accessioned 2016-10-19T05:16:14Z
dc.date.available 2016-10-19T05:16:14Z
dc.date.issued 11/17/2015
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/1927
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Masters of Pharmacy (M.Pharm) in East West University, Dhaka, Bangladesh. en_US
dc.description.abstract The drug discovery process is not a limited or established series of steps. Modern approaches include target-based drug discovery in which researchers require to survey proteins. The two most important requirements for this type of technology are to find more effective biomarkers for detecting disease and to discover proteins to which therapeutic drugs can be targeted. It is well-known that the risks in drug discovery process are high and it requires a great deal of time before it is known whether a target candidate drug will succeed or fail. The key to success for pharmaceutical companies is to make accurate decisions using an accelerated process. Genomics revolution had a very positive impact upon these issues. Proteomics is in the field, now, as a powerful new partner of genomics. It will provide a significant new aspect to drug discovery by providing the potential to analyze proteins from a very wide diversity of biological systems in a high-throughput and systematic way. Each step of the process from target discovery to clinical trials is accessible to proteomics. Scientists are able to see every detail of their biological focus, from genes, mRNA, proteins and their subcellular localization. This will greatly help our knowledge of the fundamental mechanistic basis of human disease and will assist in the discovery of improved, faster, minimum toxic and hopefully, inexpensive drugs. en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;PHA00512
dc.subject Genomics, proteomics, genes, mRNA, biomarkers, proteins. en_US
dc.title Drug Discovery Targeting Proteomic Approach en_US
dc.type Thesis en_US


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