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Determination of the Antibacterial Activity against Microorganism after Co-culture with Resistant Pathogenic Bacteria

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dc.contributor.author Tabassum, Tahsin
dc.date.accessioned 2017-06-13T04:10:57Z
dc.date.available 2017-06-13T04:10:57Z
dc.date.issued 11/25/2016
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/2172
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Masters of Pharmacy (M.Pharm) in East West University, Dhaka, Bangladesh. en_US
dc.description.abstract In this study the effect of the antibacterial activity was determined after co-culture of sensitive strain with resistant pathogenic bacteria. Disc diffusion method was used to find out the antibacterial activity after co-culture of sensitive strain with resistant pathogenic bacteria. Here, co-culture was performed with Acinetobacter baumannii and Salmonella typhi and also with Acinetobacter baumannii and Shigella flexneri. In our study, before co-culture Acinetobacter baumannii and Salmonella typhi were sensitive strains, whereas Shigella flexneri was resistant. After co-culture of two sensitive strains (Acinetobacter baumannii and Salmonella typhi), Acinetobacter baumannii showed sensitivity when treated with different concentrations (20 μg/ml, 40 μg/ml, 80 μg/ml and 160 μg/ml) of cefixime. However, no zone of inhibition was observed when Salmonella typhi was treated with different concentrations (20 μg/ml, 40 μg/ml, 80 μg/ml and 160 μg/ml) of cefixime. Co-culture of sensitive Acinetobacter baumanniiwas done with resistant Shigella flexneri. Acinetobacter baumanniis till showed sensitivity when treated with different concentrations (20 μg/ml, 40 μg/ml, 80 μg/ml and 160 μg/ml) of azithromycin. However, zone diameter was reduced to 25% when treated with azithromycin after co-culture with resistant strain of Shigella flexneri. No zone of inhibition was observed when Shigella flexneri was treated with different concentrations (20μg/ml, 40μg/ml, 80μg/ml and 160μg/ml) of azithromycin. Sensitive strain of Acinetobacter baumannii has shown 25% reduction of zone of inhibition when co-culture was done with Shigella flexneri. en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;PHA00531
dc.subject Co-culture, resistant pathogenic bacteria, Acinetobacter baumannii, Salmonella typhi, Shigella flexneri, cefixime, azithromycin en_US
dc.title Determination of the Antibacterial Activity against Microorganism after Co-culture with Resistant Pathogenic Bacteria en_US
dc.type Thesis en_US


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