Abstract:
Diabetes mellitus is a growing epidemic and is one of the most common causes of chronic
kidney disease (CKD) and kidney failure.
Large epidemiological studies have shown that one
third of the patients on hemodialysis or renal transplant recipients are diabetics, predominantly
with type 2 diabetes. Based on this evidence the aim of this survey work was to determine the
association of chronic kidney disease with diabetes mellitus in the context of Bangladesh. About
144 patients were interviewed on the predetermined questionnaire set on the objectives of this
survey work. The survey was conducted at two branches of BIRDEM hospital in Dhaka city city:
Rampura centre and Jurain centre. The majority of the survey population was female which
contributes around 60% of the population and 40% was male. Patients aged from 45 to 64,
highly suffers from diabetes mellitus and the prevalence is around 57%. The second highest
group of patients was aged above 54, where the prevalence is around 23% and 29% patient group
came from the age above 65.
The socio-economic condition of the patients was mostly average:
58% patients were from middle class, 29% people were from upper-middle class, and 13% were
from poor economical status out of 144 samples. According to this survey study people who are
suffering from diabetic mellitus for 5 or more years have the highest chance of developing
chronic kidney disease. These finding gave the indication that chronic kidney disease is
associated with long term diabetes mellitus. This research also evaluated the treatment pattern of
both diseases. Patients with diabetes mellitus mostly treated with oral anti-diabetic agent besides
insulin. Also this study result proves diabetes as the leading risk factors for chronic kidney
diseases which accounts for 48%. it is seen that majority of the patient (48%) had the HbA1C
level in between 7% to 9%. Secondly, 42% patient had their HbA1C level in below 7%. And 5%
patient had the HbA1C level in between 10% to 14% and the remaining 5% had above 14%.
Creatinine level of the chronic kidney disease patients were about (1.6-2.5) ml\dl in the majority
patients (32.6%), 1-1.5 ml/dl in the 29% patients & 0.5-0.9 ml/dl in the 28.5% patients. In
summary, this survey work gave us an updated review on the growing public health burden of
chronic kidney disease associated with diabetes mellitus in the Dhaka city.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.
