Abstract:
The goal of the study was to detect of the photosensitivity of cetirizine dihydrochloride.It was seen if there was any change of cetirizine dihydrochloride under extreme lighting conditions (25 watt,40watt,direct sunlight). In normal lighting condition degradation of cetirizine dihydrochloride was not reported. Under different extreme lighting conditions potency ceased differently with a percent deviation of 4.74% (1.47%), 7.76% (2.88%) and 16.68% (4.01%) for 25 watt,40 watt and direct sunlight..So it can be concluded that Acitrin® contanining cetirizine dihydrochloride is sensitive to extremelight and an opaque packaging is required in combination with coating to provide stability and impede degradation.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.
