In Vitro Pharmacological Investigations on Aqueous Fraction of Phyllanthus acidus Leaf Extract

Akther, Sharmin

dc.contributor.author	Akther, Sharmin
dc.date.accessioned	2017-10-10T05:40:00Z
dc.date.available	2017-10-10T05:40:00Z
dc.date.issued	7/15/2017
dc.identifier.uri	http://dspace.ewubd.edu/handle/2525/2366
dc.description	This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.	en_US
dc.description.abstract	The purpose of the study was to evaluate the cytotoxic, antioxidant and antimicrobial activity of aqueous fraction of Phyllunthus acidus leaf (Family:Phyllunthaceae) extract.The powder of leaf were extracted with methanol and then partitioned with n-hexane, DCM, and ethyl acetate, aqueous fraction was taken for experiment. The aqueous fraction was used to evaluate cytotoxic, antioxidant and antimicrobial activities. The cytotoxic activity was measured by brine shrimp lethality bioassay. LC50 value of aqueous fraction of Phyllanthus acidus was 2μg/ml in brine shrimp lethality test. The fraction contained 4.5mg AAE/g of total phenolic content and 4.868 mg AAE/g of total flavonoid content. The results of study clearly indicate the presence of cytotoxic and poor antioxidant properties of aqueous extract. The obtained results provide a support for the use of this plant in traditional medicine and its further investigation	en_US
dc.language.iso	en_US	en_US
dc.publisher	East West University	en_US
dc.relation.ispartofseries	;00610 PHA
dc.subject	Phyllanthus acidus, Brine shrimp lethality bio-assay, phenolic content, flavonoid content.	en_US
dc.title	In Vitro Pharmacological Investigations on Aqueous Fraction of Phyllanthus acidus Leaf Extract	en_US
dc.type	Thesis	en_US