In Vitro Release Pattern of Indapamide From Indapa Sustain Release Tablets

Abstract

Twenty tablets of Indapa matrix tablets were unruffled and then were characterized by physical parameters like hardness, thickness, weight variation and dissolution studies. Using the method adorned in Appendix XII B: Dissolution tests for tablets and capsules of British Pharmacopoeia, Indapamide release was explored.t8l Hardness of the withdrawn samples were calculated by hardness tester (Veego, Germany). Thickness of the samples was calculated by slide calipers. Using dissolution tester (RC6, Vanguard Pharmaceuticals, USA) dissolution of the taken samples were explored to assess release kinetics. Mean hardness value of Indapamide tablets were found to be 1.54 kg. Mean thickness value of Indapamide tablets were found to be 0.54 cm. Mean weight variation value of Indapamide tablets were found to be 0.07623 gm. We also performed dissolution test and that was the basis of our study. Various results were found from the tests and compared with the specification (British Pharmacopeias) and their standard was justified