A Literature Review of Indapamide (SR) Preparations

Abstract

The theoretical results of almost 970 published papers which were collected from different journals are reported in this work. The analysis was carried out at the research laboratory of East West University, Dhaka and data were represented to get the vital idea about the previous work and the possibilities of further work on this matter and different evaluations were performed in this research. A lot of study was done about indapamide sustained release form and collected information about the pharmacology, release profile, action of drugs, side effects and also about another important parameters. The main intension of literature review of indapamide was to set the work pattern for the research. It was tried to get some ideas about the work from different journals and the websites. The work schedule was made after the evaluations of the literatures and the experiences were implemented on the further research process. The data of the research helped a lot to get the general information's and wok. From the study I got the relationship between the increase in blood pressure and the incidence of cardiovascular disease is well recognized today. Studies have shown that more attention should be paid to systolic blood pressure (SBP) in relation to cardiovascular risk and that therapeutic interventions should preferably focus on reducing SBP. The antihypertensive efficacy of indapamide 1.5 mg sllstained release (indapamide SR), a low-dose thiazide-type diuretic, is assessed on SBP. The treatment with indapamide SR resulted in a better or equivalent control of SBP than treatment with a standard dose of a true thiazide diuretic (hydrochlorothiazide), a calcium channel blocker (amlodipine), and an angiotensinconverting enzyme inhibitor (enalapril). In conclusion, indapamide SR is very effective in lowering SBP- a major . independent cardiovascular risk factor-notably in h: pertensive high-risk patients with L VH, the elderly and diabetics, when compared to major antihypertensive treatments. This SBP-lowering effect is maintained over the long term.