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Determination of photolytic degradation of Sensit tablet (Flupentixol-Melitracen) Combination Product

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dc.contributor.author Rahman, Md. Famidur
dc.date.accessioned 2014-03-05T10:11:11Z
dc.date.available 2014-03-05T10:11:11Z
dc.date.issued 7/17/2012
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/25
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) of East West University, Dhaka, Bangladesh. en_US
dc.description.abstract Sensit tablet is a combination product of flupentixol and melitracen in which Flupentixol is neuroleptic and melitracen is anti-depressant drug. This formulation is widely used in Bangladesh in severe depression and neuralgia which have high prevalence in Bangladesh perspective. The purpose of this work is to find whether the drugs photosensitive or not. The stability of drugs in the formulation was determined by scrutinizing the potency level by spectrphotometric method and physical parameters of the tablet. Specific amounts of tablet were exposed to different environment including sunlight, florescent light and normal room condition at definite temperature. The sample then was collected at definite time interval and physical parameter and potency was later determined. All the cases, the physical parameters were within range but for potency degraded as downhill. Throughout the process this was ensured adequate drug solubility and maximum assay sensitivity. The linearity ranges for the two drugs were measured accurately with precision. From the study of the project it is concluded that the drugs Require light protection to remain stable within the shelf life. en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;PHA00261
dc.subject Pharmacy en_US
dc.title Determination of photolytic degradation of Sensit tablet (Flupentixol-Melitracen) Combination Product en_US
dc.type Thesis en_US


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