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In-Vitro Assessment Of Phenolic, Flavonoid, Flavonolic Contents And Antioxidant Activities Of Plant Pleurotus Ostreatus For Neurodegenerative Disorders

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dc.contributor.author Mridha, Mahamudul Hasan
dc.date.accessioned 2018-03-12T11:43:24Z
dc.date.available 2018-03-12T11:43:24Z
dc.date.issued 12/18/2017
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/2666
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh. en_US
dc.description.abstract Among the pathologic hypotheses of Alzheimer’s disease (AD), cholinergic deficit and oxidative stress have been implicated as two major hallmarks. Therefore, inhibition of cholinesterase and oxidation are the two promising strategies in the development of a drug for AD. Pleurotus ostreatus fungi extract is used in this research to investigate its anticholinesterase and antioxidant potentials. Anticholinesterase activity was measured by modified Ellman’s method. Antioxidant potentials were evaluated by the assay of reducing power, radical scavenging. The Methanolic extract showed strong antioxidant effect. Additionally, the extract exhibited pronounced reducing capacity. The fungi extract found moderate inhibitor of cholinesterase. The tested sample reflects potential antioxidative and moderate anticholinesterase inhibitory effect which may warrant its effectiveness in the treatment of AD. en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;PHA00716
dc.subject Phenolic, Flavonoid, Flavonolic Contents And Antioxidant Activities Of Plant Pleurotus Ostreatus For Neurodegenerative Disorders en_US
dc.title In-Vitro Assessment Of Phenolic, Flavonoid, Flavonolic Contents And Antioxidant Activities Of Plant Pleurotus Ostreatus For Neurodegenerative Disorders en_US
dc.type Thesis en_US


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