Abstract:
This research work was aimed to the determination of photolytic degradation of Flupentixol-Melitracen combination products. The objective experiment is to determine the effect of Flupentixol-Melitracen combination products in various conditions (control, sunlight, normal light, 25watt and 40watt light condition). Physical tests were performed for evaluation of hardness, thickness, weight variation, friability, of the Anzet tablets from same batch. Physical tests were performed according to the specification of USP and BP. But it was observed that the concentration of Flupentixol dihydrochloride and Melitracen hydrochloride was decreased gradually in various light condition like under 25 and 40 watt electrical bulb, sunlight exposure condition. So we can say that the Anzet containing combination of Flupentixol dihydrochloride and Melitracen hydrochloride is light sensitive and the potency is decreased after light exposure.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) of East West University, Dhaka, Bangladesh
