Evaluation of the Laxative Effects of Methanolic Extract of Spilanthes acmella

Abstract

The purpose of this study was to find medicinal use of Spilanthes acmella in indigestion and constipation. Laxatives are drugs taken to treat constipation. Laxatives work to increase the movement of feces along the colon. Constipation refers to bowel movements that are infrequent or hard to pass. Constipation is a common cause of painful defecation. Severe constipation can progress to bowel obstruction and become life-threatening. Because constipation is a symptom, not a disease, effective treatment of constipation may require first determining the cause. There are various useful plants plays important role to show antidiarrhoeal activity. There are various useful plants plays important role to show laxative effects. In this study we are paying attention on the methanolic extract of Spilanthes acmella for its laxative effects on animal models. The laxative activity of methanol extract of Spilanthes acmella at dose 200, 400 mg/kg was assessed on experimental animal and all these two doses increase the total number feces of experimental animal. It suggests that the crude extract of Spilanthes acmella possess laxative activities. It would be help us to identify the pharmacological profile of the plant extract of Spilanthes acmella.