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Variation of Flow Property of Different Set of Formulas of Excipients Against Variable Ratio of Different Diluents

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dc.contributor.author Haque, Mahjabin
dc.date.accessioned 2014-06-29T04:10:34Z
dc.date.available 2014-06-29T04:10:34Z
dc.date.issued 12/11/2013
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/682
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) of East West University, Dhaka, Bangladesh en_US
dc.description.abstract This work was proposed to determine flow properties of different set of some important pharmaceutical excipients that are most commonly used for the directly compressible tablets and to search for some equations which can predict the flow property of any set of excipients with different ratio of diluents. Different parameters to determine flow property such as Compressibility index, Hausner ratio, and angle of repose were observed for them. Many unique formulas were equipped by choosing various excipients from different classes. Diluents were mixed with these prepared formulas in different specific and justified ratio. The prepared mixture in a constant weight (5g) was then examined for measuring flow property. The values of Carr’s index, Hausner ratio and angle of repose were plotted against the percentage ratios of diluents. The study showed a linear relationship with different ratios of mixture and flow property measuring parameters. From these graphs the straightline equation for each set of formula were obtained with regression value close to 1 which can be used to predict the flow property of these formula with different ratio of diluents. Moreover the most suitable ratio of specific diluents and a specific set of other excipients were proposed that showed better flow property. en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;ENG00328
dc.subject Different Diluents en_US
dc.title Variation of Flow Property of Different Set of Formulas of Excipients Against Variable Ratio of Different Diluents en_US
dc.type Thesis en_US


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