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Test for Antinociceptive Effect of Methanolic Extract of Aegle Marmelos Bark

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dc.contributor.author Khanam, Tahmina
dc.date.accessioned 2019-02-26T09:46:12Z
dc.date.available 2019-02-26T09:46:12Z
dc.date.issued 3/28/2010
dc.identifier.uri http://dspace.ewubd.edu/handle/2525/2952
dc.description This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh. en_US
dc.description.abstract An experiment was conducted to determine the antinociceptive effect of methanolic extract of Aegle marmelos bark in swiss albino mice. The nociceptive effect was induced in test animals by administering 0.6% Acetic acid solution intraperitoneally. Control group received normal saline (10ml/kg i.p) and diclofenac (10mg/kg i.p) was used as a reference drug. The result has shown that oral administration of Aeg/e marvelous bark extract (250 mg/kg and 500 mg/kg) produced antinociception against acetic acid-induced writhing. The percent inhibition of writhing observed by the bark extract administered at a dose of 250 mg/kg was 73.89% (p=O.O); and that for the dose of 500 mg/kg was 97.34%(p=0.000008); the latter result was even higher than the data showed by the positive control diclofenac (88.49%). Therefore the present results suggest that methanolic extract of Aeg/e marmelos bark may play role in reducing pain or can that methanolic extract of Aeg/e marmelos bark may playa role in reducing en_US
dc.language.iso en_US en_US
dc.publisher East West University en_US
dc.relation.ispartofseries ;PHA00035
dc.subject methanolic extract, Aeg/e marme/os, positive control, negative control, writhing, antinociceptive. en_US
dc.title Test for Antinociceptive Effect of Methanolic Extract of Aegle Marmelos Bark en_US
dc.type Thesis en_US


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