Abstract:
The quality of pharmaceutical finished dosage forms is of major concern to the pharmaceutical
industries. An important aspect of the development of any pharmaceutical product is to maintain
the quality standards of the product. Pharmaceutical preparations take many shapes and forms
and are administered through variety of routes. Oral solid dosage forms particularly the tablet
dosage form is the most well known of all. Tablet dosage form of any pharmaceutical company
goes through many research studies and experiments to maintain the proper quality standards.
Different quality control tests are done to ensure quality product. Aim: The aim of this study was
to investigate the quality of different brands of naproxen tablets which are manufactured in
Bangladesh. Different physical parameters like hardness, thickness, friability test were conducted
to evaluate the quality of the tablets of different brands of naproxen. To assess its effectiveness
potency test was conducted. Method: Four different brands ofNaproxen 500 mg were collected
from the local market of Bangladesh. These were evaluated through the Quality control
test(Hardness, thickness, friability test& potency test).Result & discussion: The range of
hardness test result was 5-8kg. The friability test results were all in range of the standard value.
The thickness results are in range. The potency value of all brands of naproxen tablet showed the
standard value except Sonap, which is very poor (56.1%). Conclusion: Quality of a product is
the major issue for any pharmaceutical company. To ensure quality product a pharmaceutical
industry follows the international standards. So it can be said that quality is the main theme of
any product. So to maintain the proper quality, quality control parameters must be followed.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.
