Study of Pharmaceutical Equivalence of Different Brands of Naproxen(500mg)Tablet.

Abstract

The quality of pharmaceutical finished dosage forms is of major concern to the pharmaceutical industries. An important aspect of the development of any pharmaceutical product is to maintain the quality standards of the product. Pharmaceutical preparations take many shapes and forms and are administered through variety of routes. Oral solid dosage forms particularly the tablet dosage form is the most well known of all. Tablet dosage form of any pharmaceutical company goes through many research studies and experiments to maintain the proper quality standards. Different quality control tests are done to ensure quality product. Aim: The aim of this study was to investigate the quality of different brands of naproxen tablets which are manufactured in Bangladesh. Different physical parameters like hardness, thickness, friability test were conducted to evaluate the quality of the tablets of different brands of naproxen. To assess its effectiveness potency test was conducted. Method: Four different brands ofNaproxen 500 mg were collected from the local market of Bangladesh. These were evaluated through the Quality control test(Hardness, thickness, friability test& potency test).Result & discussion: The range of hardness test result was 5-8kg. The friability test results were all in range of the standard value. The thickness results are in range. The potency value of all brands of naproxen tablet showed the standard value except Sonap, which is very poor (56.1%). Conclusion: Quality of a product is the major issue for any pharmaceutical company. To ensure quality product a pharmaceutical industry follows the international standards. So it can be said that quality is the main theme of any product. So to maintain the proper quality, quality control parameters must be followed.